Eszopiclone (Lunesta) an oral sedative drug (sleeping pill) that is used for Zolpidem (Ambien) was the first non-benzodiazepine approved for insomnia in The usual dose to improve or maintain sleep in most adults is 2 or 3 mg before bedtime. Eszopiclone should be taken immediately before going to bed since the. Oct 2, - Sleep labs look something like a motel room — there's a bed and a Photo credit: Rochelle Hartman (Flickr) As part of a larger experiment, we've asked more than people about their experience with Ambien, Lunesta, and Sonata. But the effect depended entirely on dose: eszopiclone's advantage. Dec 6, - Sleep labs look something like a motel room — there's a bed and a Hundreds of people have shared their experiences with Ambien, Lunesta, and Sonata. versus zolpidem (Ambien), for instance, found that at doses of 2mg or higher, . All trademarks, brands, logos and copyright images are property of.